By G.O. Evans
Via providing history details at the choice and alertness of biochemical assessments in protection evaluation reports, this consultant seeks to supply a foundation for making improvements to the information required to intepret data.
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Additional info for Animal clinical chemistry : a primer for toxicologists
F. (1968) Drug induced modifications of laboratory test values. American Journal of Hospital Pharmacy, 25, 485–519. O. (1985) Changes of methodology and their potential effects on data banks for drug effects on clinical laboratory tests. Annals of Clinical Biochemistry, 22, 397–401. , PRINCIPE, L. & BERTI, G. 5 dichloro-2-hydroxybenzene sulphonic acid-4-aminophenazone chromogenic system in direct assay of uric acid in serum and urine. Clinical Chemistry, 26, 227–31. FUENTES-ARDERIU, X. G. (1991) Analytical goals for interference.
Potassium interference associated with sequestrenated blood, iron chelators such as desferroxamine with iron, and effects due to intramuscular injections (see Chapter 10—Cardiotoxicity and Myotoxicity). , 1974; Lindup and L’E Orme, 1981). There are many instances where xenobiotics bind to plasma proteins such as albumin but there are surprisingly few instances where this has been reported to interfere with the determination of plasma albumin. However, the binding of a test compound to proteins can have marked effects on other laboratory tests.
Fortunately, a broad range of choices will usually give a similar impression of the distribution. The stem and leaf plot is a quick way to picture the shape of a distribution while at the same time including the actual numerical values in the diagram. To make a stem and leaf plot: Statistical approaches 43 1 Separate each observation into a stem and a leaf; in general, stems may have as many digits as needed, but each leaf should contain a single digit. For example, if you have a value of 148, the stem would be 14 and the leaf 8.